Wssahickon Creek is a tributary of the Schuylkill River in Montgomery and Philadelphia Counties, Pennsylvania.

Wissahickon Creek rises in Montgomery County, runs approximately 23 miles (37 km) passing through and dividing Northwest Philadelphia before emptying into the Schuylkill River at Philadelphia. Its watershed covers about 64 square miles (170 km²).^[2]

Much of the creek now runs through or next to parkland, with the last few miles running through a deep gorge. The beauty of this area attracted the attention of literary personages like Edgar Allan Poe and John Greenleaf Whittier. The gorge area is now part of Wissahickon Valley Park in Philadelphia, and the Wissahickon Valley is known as one of 600 National Natural Landmarks of the United States